UBE2L6 抗体 (C-Term)
Quick Overview for UBE2L6 抗体 (C-Term) (ABIN388854)
抗原
See all UBE2L6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 123-153, C-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This UBE2L6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-153 amino acids from the C-terminal region of human UBE2L6.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Influenza B virus non-structural protein 1 counteracts ISG15 antiviral activity by sequestering ISGylated viral proteins." in: Nature communications, Vol. 7, pp. 12754, (2018) (PubMed).
: "Differential regulation of PML-RAR? stability by the ubiquitin ligases SIAH1/SIAH2 and TRIAD1." in: The international journal of biochemistry & cell biology, Vol. 44, Issue 1, pp. 132-8, (2011) (PubMed).
: "Mechanism for ubiquitylation of the leukemia fusion proteins AML1-ETO and PML-RARalpha." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 22, Issue 5, pp. 1369-79, (2008) (PubMed).
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: "Influenza B virus non-structural protein 1 counteracts ISG15 antiviral activity by sequestering ISGylated viral proteins." in: Nature communications, Vol. 7, pp. 12754, (2018) (PubMed).
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- UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))
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别名
- UBE2L6
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背景
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to function in the E6/E6-ap-induced ubiquitination of p53.
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分子量
- 17769
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基因ID
- 9246
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NCBI登录号
- NP_004214, NP_937826
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UniProt
- O14933
抗原
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