GDF5 抗体 (N-Term)
Quick Overview for GDF5 抗体 (N-Term) (ABIN388820)
抗原
See all GDF5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 13-41, N-Term
-
纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
-
免疫原
- This GDF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-41 amino acids from the N-terminal region of human GDF5.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- WB: 1:1000. IHC-P: 1:10~50
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
有效期
- 6 months
-
-
-
: "GDF-5 is suppressed by IL-1beta and enhances TGF-beta3-mediated chondrogenic differentiation in human rheumatoid fibroblast-like synoviocytes." in: Experimental and molecular pathology, Vol. 88, Issue 1, pp. 163-70, (2010) (PubMed).
-
: "GDF-5 is suppressed by IL-1beta and enhances TGF-beta3-mediated chondrogenic differentiation in human rheumatoid fibroblast-like synoviocytes." in: Experimental and molecular pathology, Vol. 88, Issue 1, pp. 163-70, (2010) (PubMed).
-
- GDF5 (Growth Differentiation Factor 5 (GDF5))
-
别名
- GDF5
-
背景
- GDF5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type, brachydactyly, type C, and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.
-
分子量
- 55411
-
基因ID
- 8200
-
NCBI登录号
- NP_000548
-
UniProt
- P43026
抗原
-