NEUROD1 抗体 (N-Term)
Quick Overview for NEUROD1 抗体 (N-Term) (ABIN388765)
抗原
See all NEUROD1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 15-45, N-Term
-
纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
-
免疫原
- This NeuroD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-45 amino acids from the N-terminal region of human NeuroD1.
-
亚型
- Ig Fraction
-
-
anti-Neuronal Differentiation 1 (NEUROD1) (AA 26-91) antibody
NEUROD1 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 4G12B4 unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 201-300) antibodyNEUROD1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3H8 unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 26-91) antibodyNEUROD1 适用: 人, 小鼠, 猴 ELISA 宿主: 小鼠 Monoclonal 6E9G12 unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 15-45) antibodyNEUROD1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (N-Term) antibodyNEUROD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 15-45) antibodyNEUROD1 适用: 人 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 26-91) antibodyNEUROD1 适用: 人, 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 21-120) antibodyNEUROD1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 154-356) antibodyNEUROD1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 201-300) antibodyNEUROD1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3D11 unconjugated
-
-
应用备注
- IF: 1:10~50. IF: 1:100. WB: 1:1000. IHC-P: 1:50~100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
有效期
- 6 months
-
-
- NEUROD1 (Neuronal Differentiation 1 (NEUROD1))
-
别名
- NeuroD1
-
背景
- NeuroD1 acts as a differentiation factor during neurogenesis. They are expressed transiently in a subset of neurons in the central and peripheral nervous systems at the time of their terminal differentiation. NeuroD1 is a basic helix-loop-helix (bHLH) protein contain 1 bHLH domain. NeuroD1 is a transcriptional activator, for efficient DNA binding it requires dimerization with another bHLH protein. It was reported that NeuroD1 involves heterodimerization with the ubiquitous bHLH protein E47, and regulates insulin gene expression by binding to a critical E-box motif on the insulin promoter. Defects in NEUROD1 causes maturity onset diabetes of the young type VI. MODY6 is a form of non-insulin-dependent diabetes mellitus (NIDDM) characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.
-
分子量
- 39920
-
基因ID
- 4760
-
NCBI登录号
- NP_002491
-
UniProt
- Q13562
-
途径
- Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis
抗原
-
