BMPR1A 抗体 (AA 166-195)
Quick Overview for BMPR1A 抗体 (AA 166-195) (ABIN388735)
抗原
See all BMPR1A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 166-195
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This BMPR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-195 amino acids from the Central region of human BMPR1A.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze-thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
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有效期
- 6 months
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: "The bone morphogenetic protein signaling pathway is upregulated in a mouse model of total parenteral nutrition." in: The Journal of nutrition, Vol. 139, Issue 7, pp. 1315-21, (2009) (PubMed).
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: "The bone morphogenetic protein signaling pathway is upregulated in a mouse model of total parenteral nutrition." in: The Journal of nutrition, Vol. 139, Issue 7, pp. 1315-21, (2009) (PubMed).
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- BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))
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别名
- BMPR1A
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背景
- The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
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分子量
- 60198
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基因ID
- 657
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NCBI登录号
- NP_004320
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UniProt
- P36894
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途径
- Stem Cell Maintenance
抗原
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