Isocitrate Dehydrogenase (IDH3) (AA 317-346), (C-Term) 抗体
There is 1 publication for this product available. The 兔 多克隆 anti-Isocitrate Dehydrogenase (IDH3) antibody is suitable to detect Isocitrate Dehydrogenase (IDH3) in samples from 人. It has been validated for WB.
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(1 reference)
产品编号 ABIN388634
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Quick Overview for Isocitrate Dehydrogenase (IDH3) (AA 317-346), (C-Term) 抗体 (ABIN388634)
抗原
Isocitrate Dehydrogenase (IDH3)
适用
人
宿主
兔
克隆类型
多克隆
应用范围
Western Blotting (WB)
克隆位点
RB8430
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抗原表位
- AA 317-346, C-Term
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预测反应
- B, Pr, M, Rat
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This Isocitrate dehydrogenase (IDH3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-346 amino acids from the C-terminal region of human Isocitrate dehydrogenase (IDH3).
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Novel mitochondrial substrates of omi indicate a new regulatory role in neurodegenerative disorders." in: PLoS ONE, Vol. 4, Issue 9, pp. e7100, (2009) (PubMed).
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- Isocitrate Dehydrogenase (IDH3)
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背景
- Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein described here is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.
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分子量
- 39592
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基因ID
- 3419
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NCBI登录号
- NP_005521
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UniProt
- P50213
抗原
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