TXN 抗体 (N-Term)
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北京 101111
Quick Overview for TXN 抗体 (N-Term) (ABIN388136)
抗原
See all TXN 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-30, N-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This Thioredoxin (TRX) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human Thioredoxin (TRX).
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亚型
- Ig Fraction
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anti-Thioredoxin (TXN) (AA 1-105) antibody
TXN 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 2A7 unconjugated
anti-Thioredoxin (TXN) (C-Term) antibodyTXN 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin (TXN) (AA 2-105) antibodyTXN 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin (TXN) (AA 1-105) antibodyTXN 适用: 人 WB, IHC, ICC, IP, FACS 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin (TXN) (AA 1-105) antibodyTXN 适用: 人 WB 宿主: 小鼠 Monoclonal 3# unconjugated
anti-Thioredoxin (TXN) (AA 66-94), (C-Term) antibodyTXN 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB42816 unconjugated
anti-Thioredoxin (TXN) (AA 51-105) antibodyTXN 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin (TXN) antibodyTXN 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Thioredoxin (TXN) antibodyTXN 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB7270 unconjugated
anti-Thioredoxin (TXN) (AA 1-105) antibodyTXN 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- TXN (Thioredoxin (TXN))
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别名
- Thioredoxin (TRX)
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背景
- Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide isomerase(PDI) and a number of transcription factors such as p53, NF-kB and AP-1.Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.
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分子量
- 11737
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基因ID
- 7295
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NCBI登录号
- NP_001231867, NP_003320
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UniProt
- P10599
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途径
- Carbohydrate Homeostasis, Cell RedoxHomeostasis
抗原
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