BIK 抗体 (AA 39-74)
Quick Overview for BIK 抗体 (AA 39-74) (ABIN388114)
抗原
See all BIK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 39-74
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This Bik BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-74 amino acids from human Bik BH3 Domain.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:2000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "TNF pretreatment interferes with mitochondrial apoptosis in the mouse liver by A20-mediated down-regulation of Bax." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 10, pp. 7042-9, (2007) (PubMed).
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: "TNF pretreatment interferes with mitochondrial apoptosis in the mouse liver by A20-mediated down-regulation of Bax." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 10, pp. 7042-9, (2007) (PubMed).
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- BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))
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别名
- Bik
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背景
- The Bik protein is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programmed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK.
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分子量
- 18016
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基因ID
- 638
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NCBI登录号
- NP_001188
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UniProt
- Q13323
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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