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BIK 抗体 (AA 39-74)

This 兔 多克隆 antibody specifically detects BIK in WB 和 IHC (p). It exhibits reactivity toward 人.It has been mentioned in 1 publication
产品编号 ABIN388114
发货至: 中国
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中国
北京 101111
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Room 801-803
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Quick Overview for BIK 抗体 (AA 39-74) (ABIN388114)

抗原

See all BIK 抗体
BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))

适用

  • 50
  • 14
  • 1

宿主

  • 48
  • 2

克隆类型

  • 48
  • 2
多克隆

标记

  • 33
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BIK antibody is un-conjugated

应用范围

  • 39
  • 32
  • 30
  • 13
  • 10
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB3381
  • 抗原表位

    • 20
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 39-74

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This Bik BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-74 amino acids from human Bik BH3 Domain.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:2000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Sass, Shembade, Haimerl, Lamoureux, Hashemolhosseini, Tannapfel, Tiegs: "TNF pretreatment interferes with mitochondrial apoptosis in the mouse liver by A20-mediated down-regulation of Bax." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 10, pp. 7042-9, (2007) (PubMed).

  • 抗原

    BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))

    别名

    Bik

    背景

    The Bik protein is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programmed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK.

    分子量

    18016

    基因ID

    638

    NCBI登录号

    NP_001188

    UniProt

    Q13323

    途径

    Positive Regulation of Endopeptidase Activity
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