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BCL2A1 抗体 (Ala1)

This anti-BCL2A1 antibody is a 兔 多克隆 antibody detecting BCL2A1 in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN388092
发货至: 中国

Quick Overview for BCL2A1 抗体 (Ala1) (ABIN388092)

抗原

See all BCL2A1 抗体
BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

适用

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宿主

  • 43
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克隆类型

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多克隆

标记

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This BCL2A1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB1251
  • 抗原表位

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    AA 30-65, Ala1

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This BCL2A1 (A1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-65 amino acids from human BCL2A1 (A1).

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Gollob, Sciambi, Huang, Dressman: "Gene expression changes and signaling events associated with the direct antimelanoma effect of IFN-gamma." in: Cancer research, Vol. 65, Issue 19, pp. 8869-77, (2005) (PubMed).

  • 抗原

    BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

    别名

    BCL2A1

    背景

    Bcl-2 related Protein A1 is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.

    分子量

    20132

    基因ID

    597

    NCBI登录号

    NP_001108207, NP_004040

    UniProt

    Q16548
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