SENP2 抗体 (C-Term)
Quick Overview for SENP2 抗体 (C-Term) (ABIN388045)
抗原
See all SENP2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 502-533, C-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This SENP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 502-533 amino acids from the C-terminal region of human SENP2.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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Extraembryonic but not embryonic SUMO-specific protease 2 is required for heart development." in: Scientific reports, Vol. 6, pp. 20999, (2016) (PubMed).
: "Developmental control of sumoylation pathway proteins in mouse male germ cells." in: Developmental biology, Vol. 321, Issue 1, pp. 227-37, (2008) (PubMed).
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Extraembryonic but not embryonic SUMO-specific protease 2 is required for heart development." in: Scientific reports, Vol. 6, pp. 20999, (2016) (PubMed).
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- SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
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别名
- SENP2
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背景
- SUMO is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1, SUMO2, and SUMO3 into the conjugatable mature forms and catalyze the deconjugation of these same SUMO proteins from their targeted substrates. SENP2 may also down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.
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分子量
- 67855
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基因ID
- 59343
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NCBI登录号
- NP_067640
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UniProt
- Q9HC62
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途径
- Chromatin Binding
抗原
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