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SENP2 抗体 (C-Term)

Cited in 2+ publications. This 兔 多克隆 anti-SENP2 antibody (Clone RB2705) specifically detects SENP2 in WB 和 IHC (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN388045
发货至: 中国
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Quick Overview for SENP2 抗体 (C-Term) (ABIN388045)

抗原

See all SENP2 抗体
SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))

适用

  • 48
  • 32
  • 8
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠

宿主

  • 57
  • 7

克隆类型

  • 48
  • 16
多克隆

标记

  • 26
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SENP2 antibody is un-conjugated

应用范围

  • 54
  • 27
  • 20
  • 18
  • 14
  • 13
  • 13
  • 12
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB2705
  • 抗原表位

    • 15
    • 7
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 502-533, C-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This SENP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 502-533 amino acids from the C-terminal region of human SENP2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Maruyama, Lin, Chiu, Yu, Porter, Hsu: "Extraembryonic but not embryonic SUMO-specific protease 2 is required for heart development." in: Scientific reports, Vol. 6, pp. 20999, (2016) (PubMed).

    La Salle, Sun, Zhang, Matunis, Handel: "Developmental control of sumoylation pathway proteins in mouse male germ cells." in: Developmental biology, Vol. 321, Issue 1, pp. 227-37, (2008) (PubMed).

  • 抗原

    SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))

    别名

    SENP2

    背景

    SUMO is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1, SUMO2, and SUMO3 into the conjugatable mature forms and catalyze the deconjugation of these same SUMO proteins from their targeted substrates. SENP2 may also down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.

    分子量

    67855

    基因ID

    59343

    NCBI登录号

    NP_067640

    UniProt

    Q9HC62

    途径

    Chromatin Binding
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