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Ubiquitin 抗体 (AA 36-66)

Ub 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB2702 unconjugated
产品编号 ABIN388040
发货至: 中国
  • 抗原 See all Ubiquitin (Ub) 抗体
    Ubiquitin (Ub)
    抗原表位
    • 18
    • 8
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 36-66
    适用
    • 145
    • 73
    • 72
    • 67
    • 20
    • 17
    • 17
    • 16
    • 16
    • 16
    • 12
    • 12
    • 11
    • 10
    • 10
    • 9
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 97
    • 73
    • 3
    • 1
    • 1
    克隆类型
    • 92
    • 83
    多克隆
    标记
    • 78
    • 12
    • 11
    • 10
    • 10
    • 9
    • 7
    • 7
    • 7
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Ubiquitin antibody is un-conjugated
    应用范围
    • 159
    • 84
    • 84
    • 59
    • 57
    • 46
    • 25
    • 21
    • 19
    • 13
    • 13
    • 9
    • 4
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    Y, B, E, D, Pr, M, Pig, Rat, Sh, C, Hs, Ha, X, Rb
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This Ubiquitin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-66 amino acids of human Ubiquitin.
    克隆位点
    RB2702
    亚型
    Ig Fraction
    Top Product
    Discover our top product Ub Primary Antibody
  • 应用备注
    IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Huang, Wang, Wright, Yang, Zhou, Li, Yang, Small, Parmacek: "Myocardin is required for maintenance of vascular and visceral smooth muscle homeostasis during postnatal development." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 14, pp. 4447-52, (2015) (PubMed).

    Vernes, Nicod, Elahi, Coventry, Kenny, Coupe, Bird, Davies, Fisher: "Functional genetic analysis of mutations implicated in a human speech and language disorder." in: Human molecular genetics, Vol. 15, Issue 21, pp. 3154-67, (2006) (PubMed).

  • 抗原
    Ubiquitin (Ub)
    别名
    Ubiquitin (Ub 产品)
    背景
    This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.
    分子量
    77039
    基因ID
    7314
    UniProt
    P0CG48
    途径
    Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway
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