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PRDM14 抗体 (N-Term)

Name: PRDM14 抗体 (N-Term)
SKU: ABIN388018
Availability: OutOfStock

PRDM14 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB1405 unconjugated

Western blot analysis of PRDM14 polyclonal antibody (ABIN388018 and ABIN2845429) in A549 cell lysate. (PRDM14 抗体 (N-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (PRDM14 抗体 (N-Term))

IHC (p)

IFanalysis of PRDM14 in breast cancer cells. (PRDM14 抗体 (N-Term))

3 images

(4 references)

产品编号 ABIN388018

发货至: 中国

Datasheet as PDF

抗原 See all PRDM14 抗体

PRDM14 (PR Domain Containing 14 (PRDM14))
抗原表位
7

5

2

1

1

1

1

1

1

1

1

1

1

1
AA 1-30, N-Term
适用
37

6

4

2

2

2

2

1
人
宿主
31

3

2

1
兔
Compatible Secondaries
克隆类型
34

3
多克隆
标记
22

3

2

2

1

1

1

1

1

1

1

1
This PRDM14 antibody is un-conjugated
应用范围
24

19

18

13

10

4

3

3

2

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This PRDM14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PRDM14.

克隆位点

RB1405

亚型

Ig Fraction

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PRDM14 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 6H9F1 unconjugated

anti-PR Domain Containing 14 (PRDM14) (N-Term) antibody
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anti-PR Domain Containing 14 (PRDM14) (AA 301-571) antibody
PRDM14 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-PR Domain Containing 14 (PRDM14) antibody
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anti-PR Domain Containing 14 (PRDM14) (AA 208-257) antibody
PRDM14 适用: 人, Pig, Cow, 兔, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-PR Domain Containing 14 (PRDM14) (AA 414-427) antibody
Verified PRDM14 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-PR Domain Containing 14 (PRDM14) antibody
PRDM14 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IP, ChIP, IC 宿主: 兔 Polyclonal unconjugated

anti-PR Domain Containing 14 (PRDM14) (AA 533-544) antibody
Verified PRDM14 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

应用备注

IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Sugawa, Araúzo-Bravo, Yoon, Kim, Aramaki, Wu, Stehling, Psathaki, Hübner, Schöler: "Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile." in: The EMBO journal, Vol. 34, Issue 8, pp. 1009-24, (2015) (PubMed).

Tsuneyoshi, Sumi, Onda, Nojima, Nakatsuji, Suemori: "PRDM14 suppresses expression of differentiation marker genes in human embryonic stem cells." in: Biochemical and biophysical research communications, Vol. 367, Issue 4, pp. 899-905, (2008) (PubMed).

Watanabe, Toyota, Kondo, Suzuki, Imai, Ohe-Toyota, Maruyama, Nojima, Sasaki, Sekido, Hiratsuka, Shinomura, Imai, Itoh, Tokino: "PRDM5 identified as a target of epigenetic silencing in colorectal and gastric cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 16, pp. 4786-94, (2007) (PubMed).

Nishikawa, Toyota, Suzuki, Honma, Fujikane, Ohmura, Nishidate, Ohe-Toyota, Maruyama, Sonoda, Sasaki, Urano, Imai, Hirata, Tokino: "Gene amplification and overexpression of PRDM14 in breast cancers." in: Cancer research, Vol. 67, Issue 20, pp. 9649-57, (2007) (PubMed).
抗原

PRDM14 (PR Domain Containing 14 (PRDM14))

别名

PRDM14 (PFM11) (PRDM14 产品)

别名

PFM11 antibody, PRDM14 antibody, prmd14 antibody, fc16b12 antibody, wu:fc16b12 antibody, PR/SET domain 14 antibody, PR domain containing 14 antibody, PRDM14 antibody, Prdm14 antibody, prdm14 antibody

背景

Similar to acetylation and phosphorylation, histone methylation at the N terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET domain containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET domain family, and another 17 make up the PR domain family that is related to the SET domain family. PRDM14 is part of a family of PR domain genes that are involved in tumorigenesis. It may function as a transcription factor.

分子量

64062

基因ID

63978

NCBI登录号

NP_078780

UniProt

Q9GZV8