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DNMT3A 抗体 (C-Term)

This anti-DNMT3A antibody is a 兔 多克隆 antibody detecting DNMT3A in WB. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN387865
发货至: 中国

Quick Overview for DNMT3A 抗体 (C-Term) (ABIN387865)

抗原

See all DNMT3A 抗体
DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

适用

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宿主

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克隆类型

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多克隆

标记

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This DNMT3A antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB12504
  • 抗原表位

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    AA 723-752, C-Term

    预测反应

    M, Rat

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This Dnmt3A/Dnmt3A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 723-752 amino acids from the C-terminal region of human Dnmt3A/Dnmt3A2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • ODoherty, OShea, Sandra, Lonergan, Fair, Forde: "Imprinted and DNA methyltransferase gene expression in the endometrium during the pre- and peri-implantation period in cattle." in: Reproduction, fertility, and development, Vol. 29, Issue 9, pp. 1729-1738, (2018) (PubMed).

    ODoherty, OShea, Fair: "Bovine DNA methylation imprints are established in an oocyte size-specific manner, which are coordinated with the expression of the DNMT3 family proteins." in: Biology of reproduction, Vol. 86, Issue 3, pp. 67, (2012) (PubMed).

  • 抗原

    DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

    别名

    Dnmt3A/Dnmt3A2

    背景

    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. DNMT3A is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.

    分子量

    101858

    基因ID

    1788

    NCBI登录号

    NP_072046, NP_715640, NP_783328, NP_783329

    UniProt

    Q9Y6K1
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