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SOX2 抗体

Cited in 4+ publications. The 小鼠 单克隆 anti-SOX2 antibody (Clone 57CT23-3-4) (ABIN387798) specifically detects SOX2 in WB, IF, FACS 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN387798
发货至: 中国
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Quick Overview for SOX2 抗体 (ABIN387798)

抗原

See all SOX2 抗体
SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This SOX2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

57CT23-3-4
  • 纯化方法

    This antibody is purified through a protein G column, followed by dialysis against PBS.

    免疫原

    SOX2 recombinant protein is used to produce this monoclonal antibody.

    亚型

    IgG1
  • 应用备注

    IF: 1:100. IF: 1:10~50. WB: 1:200~2000. WB: 1:200~2000. WB: 1:1000. WB: 1:4000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze-thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

    有效期

    6 months
  • Chen, Ou, Song, Xian, Ouyang, Xie, Xue, Sun: "Generation of integration-free induced pluripotent stem cells (GZHMUi001-A) by reprogramming peripheral blood mononuclear cells from a 47, XXX syndrome patient." in: Stem cell research, Vol. 23, pp. 57-60, (2018) (PubMed).

    Horibe, Hirohashi, Asano, Mariya, Suzuki, Takaya, Saijo, Shionoya, Kubo, Nakatsugawa, Kanaseki, Tsukahara, Watanabe, Atsuyama, Toji, Hirano, Hasegawa, Takahashi, Sato, Torigoe: "Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is a novel target of lung cancer stem-like cell immunotherapy." in: PLoS ONE, Vol. 12, Issue 3, pp. e0171460, (2017) (PubMed).

    Zheng, Pang, Gu, Gao, Zhang, Pang, Liu: "Melatonin Inhibits Glioblastoma Stem-like cells through Suppression of EZH2-NOTCH1 Signaling Axis." in: International journal of biological sciences, Vol. 13, Issue 2, pp. 245-253, (2017) (PubMed).

    Tilson, Haley, Triantafillu, Dozier, Langford, Gillespie, Kim: "ROCK Inhibition Facilitates In Vitro Expansion of Glioblastoma Stem-Like Cells." in: PLoS ONE, Vol. 10, Issue 7, pp. e0132823, (2015) (PubMed).

  • 抗原

    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

    别名

    SOX2

    背景

    This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

    分子量

    34310

    基因ID

    6657

    NCBI登录号

    NP_003097

    UniProt

    P48431

    途径

    Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
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