PRDM2 抗体 (AA 1-347)
Quick Overview for PRDM2 抗体 (AA 1-347) (ABIN387783)
抗原
See all PRDM2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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    - 
                                            抗原表位
- AA 1-347
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                                            纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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                                            免疫原
- Purified recombinant GST fusion protein encoding aa 1-347 of human RIZ1. This antibody is specific for RIZ1, it does not recognize the isoform beta (RIZ2).
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                                            亚型
- IgG1
 
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                                            应用备注
- CHIP: 1:100. CHIP: 1:100. CHIP: 1:100. WB: 1:1000
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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                                            有效期
- 6 months
 
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    - 
                                            : "RIZ1 is potential CML tumor suppressor that is down-regulated during disease progression."    in: Journal of hematology & oncology, Vol. 2, pp. 28, (2009)         (PubMed).        
 : "A histone methyltransferase is required for maximal response to female sex hormones." in: Molecular and cellular biology, Vol. 24, Issue 16, pp. 7032-42, (2004) (PubMed).
 
 
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                                            : "RIZ1 is potential CML tumor suppressor that is down-regulated during disease progression."    in: Journal of hematology & oncology, Vol. 2, pp. 28, (2009)         (PubMed).        
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    - PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))
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                                            别名
- PRDM2 (RIZ1)
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                                            背景
- This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.
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                                            分子量
- 188915
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                                            基因ID
- 7799
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                                            NCBI登录号
- NP_001007258, NP_001129082, NP_036363, NP_056950
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                                            UniProt
- Q13029
 抗原
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