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BCL10 抗体 (AA 122-168)

The 小鼠 单克隆 anti-BCL10 antibody is suitable to detect BCL10 in samples from 人.
产品编号 ABIN379257
发货至: 中国
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Quick Overview for BCL10 抗体 (AA 122-168) (ABIN379257)

抗原

See all BCL10 抗体
BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This BCL10 antibody is un-conjugated

应用范围

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克隆位点

151
  • 抗原表位

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    AA 122-168

    特异性

    Monoclonal Anti-Bcl-10 reacts specifically with human Bcl-10. The epitope recognized by the antibody resides within amino acids 122-168 of human Bcl-10 Molecule. Bcl-10, also designated as CIPER, mE10, cE10, CARMEN, and CLAP, is an N-terminal CARD (Caspase Recruitment Domain) containing protein. It is a cellular homologue of the equine herpesvirus-2 protein E-10 (vCLAP). Bcl-10 was implicated in the regulation of apoptosis by interacting with caspase 9, enhancing procaspase 9 processing, and triggering its activation when overexpressed in the cell. Bcl-10 cellular overexpression induces JNK, p38, and NF-kB activation. Deregulation of Bcl-10 expression is also demonstrated to be involved in cellular oncogenesis.

    纯化方法

    Protein G purified

    免疫原

    Human recombinant Bcl-10.

    亚型

    IgG1
  • 说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Buffer contains: 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • 抗原

    BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

    别名

    BCL10 / BCL-10

    背景

    Name/Gene ID: BCL10
    Family: Apoptosis

    Synonyms: BCL10, Bcl-10, B-cell CLL/lymphoma 10, B-cell lymphoma/leukemia 10, CARMEN, CARD-like apoptotic protein, CCARMEN, C-E10, CIPER, Cellular-E10, HCLAP, Cellular homolog of vCARMEN, CLAP, ME10

    基因ID

    8915

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
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