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CD22 抗体 (APC)

This anti-CD22 antibody is a 大鼠 单克隆 antibody detecting CD22 in FACS. Suitable for 小鼠.
产品编号 ABIN375781
发货至: 中国

Quick Overview for CD22 抗体 (APC) (ABIN375781)

抗原

See all CD22 抗体
CD22 (CD22 Molecule (CD22))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD22 antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)

克隆位点

2D6
  • 特异性

    Mouse CD22, Mr 150 kDa

    产品特性

    Rat Anti-Mouse CD22-APC

    纯化方法

    Purified

    免疫原

    Splenic lymphocyte plasma membranes from CBA x C57 F1 mice

    亚型

    IgG1
  • 应用备注

    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , Activ - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

    样本量

    1 mL

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze!
    Protect conjugated products from light.

    Each reagent is stable for the period shown on the bottle label if stored as directed.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C
  • 抗原

    CD22 (CD22 Molecule (CD22))

    别名

    CD22

    背景

    CD22, also known as Lyb-8, is a heterodimeric transmembrane glycoprotein and a member of a structurally related group of immunoglobulin (Ig) superfamily domain-containing proteins called the sialoadhesin family. It is detected in the cytoplasm early in B cell development (late pro-B cell stage), appears on the cell surface concomitant with IgD, and is found on most IgM + IgD + mature B lymphocytes. Expression is lost with terminal differentiation of B cells and is absent on plasma cells. Activation of B cells via cross-linking of surface Ig increases CD22 expression. CD22 associates with the B cell receptor (BCR) complex and mediates intercellular adhesion. Its intracellular domain is phosphorylated after antigen receptor cross- linking and is involved in negative regulation of B-cell activation.
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