ITGA4 抗体 (PE)
Quick Overview for ITGA4 抗体 (PE) (ABIN375534)
抗原
See all ITGA4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Mouse/Human CD49d, Mr 150 kDa
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产品特性
- Rat Anti-Mouse CD49d-PE
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纯化方法
- Purified
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免疫原
- P815 cells
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亚型
- IgG2b
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应用备注
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- Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Adhesion - Reported in literature , Block - Reported in literature
- Working Dilutions: Flow Cytometry FITC and BIOT conjugates 2 g/106 cells PE conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
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样本量
- 2 mL
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- 0.1 mg in 1.0 mL or 0.2 mg in 2.0 mL of PBS/Sodium azide and a stabilizing agent
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
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Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed. -
储存条件
- 4 °C
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储存方法
- Store at 2-8°C
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Cell circuits between B cell progenitors and IL-7+ mesenchymal progenitor cells control B cell development." in: The Journal of experimental medicine, Vol. 215, Issue 10, pp. 2586-2599, (2018) (PubMed).
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Cell circuits between B cell progenitors and IL-7+ mesenchymal progenitor cells control B cell development." in: The Journal of experimental medicine, Vol. 215, Issue 10, pp. 2586-2599, (2018) (PubMed).
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- ITGA4 (Integrin alpha 4 (ITGA4))
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别名
- CD49d
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背景
- VLA-4 belongs to the β 1 -integrin family, which functions both as cell-matrix and cell-cell receptors. As a matrix receptor VLA-4 binds to an alternatively spliced domain of fibronectin, while as a cellular receptor it associates with its counter-receptor ligand VCAM-1. In addition to CD44/pgp-1, VLA-4 has been shown to be important for lymphopoiesis, and is also believed to be important for extravasation of lymphocytes into sites of inflammation as a second signal in addition to LFA/ICAM-1. CD49d/VLA-4 is expressed in low amounts on resting lymphocytes and monocytes, is absent or minimally detectable on stromal cells, whereas virtually all lymphoid and myeloid cells in bone marrow and in long-term culture are positive.
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途径
- Integrin Complex
抗原
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