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ITGA4 抗体 (PE)

This anti-ITGA4 antibody is a 大鼠 单克隆 antibody detecting ITGA4 in FACS. Suitable for 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN375534
发货至: 中国

Quick Overview for ITGA4 抗体 (PE) (ABIN375534)

抗原

See all ITGA4 抗体
ITGA4 (Integrin alpha 4 (ITGA4))

适用

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小鼠

宿主

  • 76
  • 58
  • 27
大鼠

克隆类型

  • 100
  • 62
  • 2
单克隆

标记

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This ITGA4 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

PS-2
  • 特异性

    Mouse/Human CD49d, Mr 150 kDa

    产品特性

    Rat Anti-Mouse CD49d-PE

    纯化方法

    Purified

    免疫原

    P815 cells

    亚型

    IgG2b
  • 应用备注

    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Adhesion - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 2 g/106 cells PE conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

    样本量

    2 mL

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    0.1 mg in 1.0 mL or 0.2 mg in 2.0 mL of PBS/Sodium azide and a stabilizing agent

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze!
    Protect conjugated products from light.

    Each reagent is stable for the period shown on the bottle label if stored as directed.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C
  • Fistonich, Zehentmeier, Bednarski, Miao, Schjerven, Sleckman, Pereira: "Cell circuits between B cell progenitors and IL-7+ mesenchymal progenitor cells control B cell development." in: The Journal of experimental medicine, Vol. 215, Issue 10, pp. 2586-2599, (2018) (PubMed).

  • 抗原

    ITGA4 (Integrin alpha 4 (ITGA4))

    别名

    CD49d

    背景

    VLA-4 belongs to the β 1 -integrin family, which functions both as cell-matrix and cell-cell receptors. As a matrix receptor VLA-4 binds to an alternatively spliced domain of fibronectin, while as a cellular receptor it associates with its counter-receptor ligand VCAM-1. In addition to CD44/pgp-1, VLA-4 has been shown to be important for lymphopoiesis, and is also believed to be important for extravasation of lymphocytes into sites of inflammation as a second signal in addition to LFA/ICAM-1. CD49d/VLA-4 is expressed in low amounts on resting lymphocytes and monocytes, is absent or minimally detectable on stromal cells, whereas virtually all lymphoid and myeloid cells in bone marrow and in long-term culture are positive.

    途径

    Integrin Complex
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