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CD86 抗体 (PE)

This anti-CD86 antibody is a 大鼠 单克隆 antibody detecting CD86 in FACS. Suitable for 小鼠.
产品编号 ABIN375529
发货至: 中国

Quick Overview for CD86 抗体 (PE) (ABIN375529)

抗原

See all CD86 抗体
CD86

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD86 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

2D10
  • 特异性

    Mouse CD86, Mr 80 kDa

    产品特性

    Rat Anti-Mouse CD86-PE

    纯化方法

    Purified

    免疫原

    Mouse B cell lymphoma cell line 5C2

    亚型

    IgG2b
  • 应用备注

    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Block - Reported in literature , Sep - Reported in literature , CMCD - Reported in literature , ELISA - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE, APC, SPRD, and PE/CY7 conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

    说明

    In vivo and in vitro blocking assays, Identification of CD86+ cells in frozen section

    样本量

    1 mL

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze!
    Protect conjugated products from light.

    Each reagent is stable for the period shown on the bottle label if stored as directed.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C
  • 抗原

    CD86

    别名

    CD86

    背景

    CD86/B7-2 is an 80 kDa type I integral membrane protein and a member of the immunoglobulin superfamily of cell surface receptors. Along with CD80/B7-1, CD86 participates in T cell costimulation via interaction with CD28 and CD152/CTLA-4. It is expressed at very low density in normal tissues but is rapidly upregulated on stimulated B cells, monocytes and dendritic cells. Since CD86/B7-2 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response.

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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