CD8 alpha 抗体
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北京 101111
Quick Overview for CD8 alpha 抗体 (ABIN375493)
抗原
See all CD8 alpha (CD8A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Rat Anti-Mouse CD8α-LE/AF
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特异性
- Mouse CD8α, Mr 32-34 kDa
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产品特性
- Low Endotoxin/Azide Free Anti-Mouse CD8 alpha antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, depletion, and blocking assays.
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内毒素水平
- Low Endotoxin
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免疫原
- Spleen cells or thymocyte membranes
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate buffered saline, pH 7.4
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储存液
- Azide free
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注意事项
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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储存条件
- 4 °C
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储存方法
- 2-8°C
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- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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别名
- CD8alpha
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背景
- In the mouse, CD8 exists in two forms: (i) a CD8 heterodimer composed of an α chain (CD8 α /Lyt-2) and a β chain (CD8 β /Lyt-3), and (ii) a homodimer of two α chains. The heterodimer is found on the surface of essentially all thymocytes and the 'suppressor/cytotoxic' subpopulation of mature T lymphocytes. Subsets of intestinal intraepithelial lymphocytes express CD8 α without CD8 β. It has been suggested that CD8 + β - T cells mature extrathymically, while development of the CD8 α + β + population of T cells is thymus-dependent. CD8 acts as a coreceptor with MHC Class I-restricted T cell receptors in antigen recognition and positive selection of MHC class I-restricted CD8 + T cells
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基因ID
- 12525
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UniProt
- P01731
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途径
- TCR Signaling
抗原
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