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CD8 alpha 抗体

This 大鼠 单克隆 antibody specifically detects CD8 alpha in FACS, IP, ICC, IHC (fro), BR 和 Dep. It exhibits reactivity toward 小鼠.
产品编号 ABIN375493
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD8 alpha 抗体 (ABIN375493)

抗原

See all CD8 alpha (CD8A) 抗体
CD8 alpha (CD8A) (CD8a Molecule (CD8A))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD8 alpha antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR), Depletion (Dep)

克隆位点

53-6-7
  • 原理

    Rat Anti-Mouse CD8α-LE/AF

    特异性

    Mouse CD8α, Mr 32-34 kDa

    产品特性

    Low Endotoxin/Azide Free Anti-Mouse CD8 alpha antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, depletion, and blocking assays.

    内毒素水平

    Low Endotoxin

    免疫原

    Spleen cells or thymocyte membranes

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Phosphate buffered saline, pH 7.4

    储存液

    Azide free

    注意事项

    Each reagent is stable for the period shown on the bottle label if stored as directed.

    储存条件

    4 °C

    储存方法

    2-8°C
  • 抗原

    CD8 alpha (CD8A) (CD8a Molecule (CD8A))

    别名

    CD8alpha

    背景

    In the mouse, CD8 exists in two forms: (i) a CD8 heterodimer composed of an α chain (CD8 α /Lyt-2) and a β chain (CD8 β /Lyt-3), and (ii) a homodimer of two α chains. The heterodimer is found on the surface of essentially all thymocytes and the 'suppressor/cytotoxic' subpopulation of mature T lymphocytes. Subsets of intestinal intraepithelial lymphocytes express CD8 α without CD8 β. It has been suggested that CD8 + β - T cells mature extrathymically, while development of the CD8 α + β + population of T cells is thymus-dependent. CD8 acts as a coreceptor with MHC Class I-restricted T cell receptors in antigen recognition and positive selection of MHC class I-restricted CD8 + T cells

    基因ID

    12525

    UniProt

    P01731

    途径

    TCR Signaling
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