H2-D1 抗体
Quick Overview for H2-D1 抗体 (ABIN375490)
抗原
See all H2-D1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Mouse H-2Db
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产品特性
- Mouse Anti-Mouse H-2Db-LE/AF
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纯化方法
- Purified
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内毒素水平
- Low endotoxin
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免疫原
- C3H.SW mouse splenocytes
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亚型
- IgG2a
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应用备注
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- Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Block - Reported in literature , CMCD - Reported in literature
- Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, and AF488 conjugates 1 g/106 cells PE conjugate 0.5 g/106 cells APC conjugate 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
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说明
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Complement-mediated cytotoxicity
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样本量
- 1 mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- 0.5 mg of purified immunoglobulin in 1.0 mL of PBS
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储存液
- Azide free
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注意事项
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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储存条件
- -20 °C
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储存方法
- Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
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- H2-D1 (Histocompatibility 2, D Region Locus 1 (H2-D1))
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别名
- H-2Db
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背景
- The 'classical' MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic α chains noncovalently associated with the invariant β 2-microglobulin. These antigens are expressed on most nucleated cells but expression varies on different cell types. MHC Class I molecules present endogenously synthesized peptides to CD8 + T lymphocytes, which are usually cytotoxic T cells. MHC Class I antigens expressed on thymic epithelial cells regulate the positive and negative selection of CD8 + T cells during T cell ontogeny.
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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