ICAM1 抗体
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- 抗原 See all ICAM1 抗体
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This ICAM1 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 特异性
- Mouse/Porcine CD54, Mr 95 kDa
- 产品特性
- Rat Anti-Mouse CD54-LE/AF
- 纯化方法
- Purified
- 内毒素水平
- Low endotoxin
- 免疫原
- Mouse NS-1 cells
- 克隆位点
- YN1-1-7-4
- 亚型
- IgG2b
- Top Product
- Discover our top product ICAM1 Primary Antibody
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- 应用备注
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- Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , WB - Reported in literature , IP - Reported in literature , Block - Reported in literature , Purification - Reported in literature
- Working Dilutions: Flow Cytometry FITC, BIOT, AF488, and PACBLU conjugates 1 g/106 cells PE, APC, AF647, and AF700 conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- 说明
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In vitro blocking studies
- 样本量
- 1 mL
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- 0.5 mg of purified immunoglobulin in 1.0 mL of PBS
- 储存液
- Azide free
- 注意事项
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- 储存条件
- -20 °C
- 储存方法
- Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
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- 抗原
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
- 别名
- CD54 (ICAM1 产品)
- 物质类
- Viral Protein
- 背景
- CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes and lymphocytes. Its expression is upregulated by inflammatory mediators such as IFN- γ, IL-1, TNF- α, lipopolysaccharide and phorbol esters. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels, particularly in areas of inflammation. CD54 on antigen-presenting cells contributes to antigen-specific T-cell activation, presumably by enhancing interactions between T cell and antigen-presenting cells. These adhesion reactions are mediated via the binding of CD54 to its major ligands, LFA-1 and Mac-1.
- 途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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