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CD45.1 抗体 (APC-Cy7)

适用: 小鼠 FACS 宿主: 小鼠 Monoclonal A20 APC-Cy7
产品编号 ABIN375420
发货至: 中国
  • 抗原 See all CD45.1 products
    CD45.1 (CD45 (CD45.1 Allogen))
    适用
    小鼠
    宿主
    • 44
    小鼠
    克隆类型
    • 44
    单克隆
    标记
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD45.1 antibody is conjugated to APC-Cy7
    应用范围
    • 44
    • 13
    • 11
    • 6
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    特异性
    Mouse CD45.1, Mr 180-240 kDa
    产品特性
    Mouse Anti-Mouse CD45.1-APC/CY7
    纯化方法
    Purified
    免疫原
    SJL mouse thymocytes and splenocytes
    克隆位点
    A20
    亚型
    IgG2a
  • 应用备注
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature
    • Working Dilutions: Flow Cytometry FITC, BIOT, and AF488 conjugates 1 g/106 cells PACBLU conjugate 0.3 g/106 cells PE, APC, SPRD, CY5, PE/CY5.5, PE/CY7, APC/CY5.5, 0.2 g/106 cells APC/CY7, and AF647 conjugates For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    样本量
    1 mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    0.1 mg in 0.2 mL of PBS/Sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze!
    Protect conjugated products from light.

    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C
  • 抗原
    CD45.1 (CD45 (CD45.1 Allogen))
    别名
    CD45.1 (CD45.1 产品)
    背景
    The CD45 antigen is an essential regulator of leukocyte activation and development, and is now known to be a protein tyrosine phosphatase, e.g. CD45 is able to dephosphorylate the Src family of protein kinases. This activity is now known to be required for signal transduction induced by T and B cell antigen receptor engagement, cytokine signaling and Fc receptor stimulation. The functional state of CD45 also has a pronounced effect on lymphocyte development. CD45 exists in multiple forms, such as the restricted variants (CD45R) and as allelic forms CD45.1/Ly-5.1 and CD45.2/Ly-5.2. The former arises as a result of alternative splicing of different exons. The specificity of antibodies to CD45.1 and CD45.2 has been exploited in studies where resolution of donor and recipient cells is essential, such as in gene therapy or bone marrow transplantation.
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