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CNTF Receptor alpha 抗体 (Internal Region)

The 山羊 多克隆 anti-CNTF Receptor alpha antibody is suitable to detect CNTF Receptor alpha in samples from 小鼠. It has been validated for WB 和 EIA.
产品编号 ABIN375185
发货至: 中国
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Quick Overview for CNTF Receptor alpha 抗体 (Internal Region) (ABIN375185)

抗原

See all CNTF Receptor alpha (CNTFR) 抗体
CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

适用

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小鼠

宿主

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山羊

克隆类型

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多克隆

标记

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This CNTF Receptor alpha antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Internal Region

    特异性

    This antibody reacts to CNTFR.

    交叉反应 (详细)

    Species reactivity (expected):Human, Rat, Canine.
    Species reactivity (tested):Mouse.

    纯化方法

    Affinity chromatography

    免疫原

    Peptide with sequence CRSNTYPKGFY, from the internal region of the protein sequence
  • 应用备注

    Peptide ELISA: 1/16000. Western Blot: 0.3 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0,5 mg/mL

    缓冲液

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

    别名

    CNTFR

    背景

    CNTF Receptor alpha is a receptor belonging to the cytokine superfamily of receptors. Along with LIFR and gp130, CNTF Receptor alpha forms the heterotrimeric CNTF receptor complex. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. During signal transduction, CNTF first binds to CNTF Recepror alpha, and this permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified.Synonyms: CNTFR, CNTFR alpha, Ciliary neurotrophic factor receptor alpha

    基因ID

    12804

    NCBI登录号

    NP_001129528

    UniProt

    O88507

    途径

    JAK/STAT Signaling, Feeding Behaviour
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