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BIN1 抗体 (Internal Region)

This 山羊 多克隆 antibody specifically detects BIN1 in WB 和 EIA. It exhibits reactivity toward 人.
产品编号 ABIN375175
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BIN1 抗体 (Internal Region) (ABIN375175)

抗原

See all BIN1 抗体
BIN1 (Bridging Integrator 1 (BIN1))

适用

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  • 38
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  • 1
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宿主

  • 57
  • 17
  • 1
山羊

克隆类型

  • 41
  • 34
多克隆

标记

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  • 3
  • 3
  • 3
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This BIN1 antibody is un-conjugated

应用范围

  • 61
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  • 5
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  • 2
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  • 1
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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 7
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    • 2
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    • 1
    • 1
    • 1
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    • 1
    • 1
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    Internal Region

    特异性

    This antibody reacts to BIN1.

    交叉反应 (详细)

    Species reactivity (expected):Mouse, Rat, Bovine.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    免疫原

    Peptide with sequence C-SDNAPAKGNKSPS, from the internal region of the protein sequence
  • 应用备注

    Peptide ELISA: 1/1000. Western Blot: 1 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0,5 mg/mL

    缓冲液

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    BIN1 (Bridging Integrator 1 (BIN1))

    别名

    BIN1 / AMPHL

    背景

    The identification and analysis of tumor suppressors is of major importance for improved diagnosis and treatment of tumors. Bin1 (Box-dependent myc interacting protein 1, also known as SH3P9, amphiphysin II and amphl/amphiphysin-like) is a novel protein that has features of a tumor suppressor. Bin1 interacts with and inhibits the oncogenic activity of the myc oncoprotein that has a major role in many human cancers. The loss of Bin1 may contribute to growth deregulation in cancer cells in carcinoma of the breast, colon, lung, cervix, prostate and liver. Bin1 also interacts with HCV NS5A through its SH3 domain.Synonyms: Amphiphysin II, Amphiphysin-like protein, Box-dependent myc-interacting protein 1, Bridging integrator 1, Myc box-dependent-interacting protein 1

    基因ID

    274

    NCBI登录号

    NP_004296

    UniProt

    O00499
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