Biglycan 抗体 (C-Term)
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北京 101111
Quick Overview for Biglycan 抗体 (C-Term) (ABIN375174)
抗原
See all Biglycan (BGN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- C-DRLAIQFGNY KK
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特异性
- This antibody recognizes Biglycan Preproprotein.
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交叉反应 （详细）
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Species reactivity (expected):Mouse, Canine.
Species reactivity (tested):Human, Rat. -
纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
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免疫原
- Synthetic peptide from the C-Terminus of Human Biglycan (NP_001702.1) Genename: BGN
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anti-Biglycan (BGN) (AA 1-368) antibody
BGN 适用: 人 WB, IP, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4E1-1G7 unconjugated
anti-Biglycan (BGN) (AA 230-366) antibodyBGN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Biglycan (BGN) (AA 53-166) antibodyBGN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Biglycan (BGN) (C-Term) antibodyVerified BGN 适用: 人, 小鼠 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Biglycan (BGN) (AA 101-200) antibodyBGN 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Biglycan (BGN) (AA 148-176) antibodyBGN 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19735 unconjugated
anti-Biglycan (BGN) (AA 38-300) antibodyBGN 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Biglycan (BGN) (AA 1-368) antibodyBGN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Biglycan (BGN) (C-Term) antibodyBGN 适用: 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Biglycan (BGN) (AA 20-230) antibodyBGN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Peptide ELISA: 1/8000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Biglycan (BGN)
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别名
- Biglycan
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背景
- Biglycan is an extracellular matrix proteoglycan that is closely related in structure to decorin and fibromodulin. Biglycan and decorin are thought to be the result of a gene duplication. Biglycan is expressed in secondary myotubes during fetal muscle formation. In adult muscle it is located in the endomysium and neuromuscular junctions, where it connects to the dystrophin-associated proteins through binding to a-dystroglycan. In developing newborn mice biglycan expression is initially high and then decreases during skeletal muscle differentiation and maturation. Biglycan may also have a role in the fibrotic process since it is overexpressed in atherosclerotic lesions and has been shown to cause an increase in thymidine incorporation and migration of vascular smooth muscle cells.Synonyms: BGN, Bone/cartilage proteoglycan I, PG-S1, PGS1, SLRR1A, Small Leucine-rich Protein 1A
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分子量
- 41.7 kDa (Human NP_001702.1 and Rat NP_058783.1)
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基因ID
- 633
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NCBI登录号
- NP_001702
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UniProt
- P21810
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途径
- Glycosaminoglycan Metabolic Process
抗原
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