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APOA5 抗体 (C-Term)

This 山羊 多克隆 antibody specifically detects APOA5 in WB 和 EIA. It exhibits reactivity toward 人.
产品编号 ABIN375169
发货至: 中国
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Quick Overview for APOA5 抗体 (C-Term) (ABIN375169)

抗原

See all APOA5 抗体
APOA5 (Apolipoprotein A-V (APOA5))

适用

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宿主

  • 68
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山羊

克隆类型

  • 72
  • 20
多克隆

标记

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This APOA5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 9
    • 6
    • 5
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    • 1
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    C-Term

    特异性

    This antibody reacts to APOA5.

    纯化方法

    Affinity chromatography

    免疫原

    Peptide with sequence C-HSLHDQGHSHLGDP, from the C Terminus of the protein sequence
  • 应用备注

    Peptide ELISA: 1/64000. Western Blot: 0.3 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0,5 mg/mL

    缓冲液

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    APOA5 (Apolipoprotein A-V (APOA5))

    别名

    Apolipoprotein A V (ApoA V)

    背景

    Apolipoprotein A V is a minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. It may also be associated with chylomicrons. It is an important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and a inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate). Apolipoprotein A V activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages. Apolipoprotein A V is upregulated by PPARA agonists, which are used clinically to lower serum TG (such as fibrates). It is induced in early phase of liver regeneration. Defects in Apolipoprotein A V gene are a cause of susceptibility to familial hypertriglyceridemia. It is a coronary heart disease risk factor. On a regular diet the patient demonstrates increased plasma VLDL. Plasma triglycerides are persistently increased, while plasma cholesterol and phospholipids are usually within normal limits.Synonyms: APOA5, Apo-AV, ApoA-V, Apolipoprotein A-V, RAP3, Regeneration-associated protein 3

    基因ID

    116519, 9606

    UniProt

    Q6Q788

    途径

    Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
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