GCKR 抗体 (N-Term)
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Quick Overview for GCKR 抗体 (N-Term) (ABIN375154)
抗原
See all GCKR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts to GCKR.
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交叉反应 (详细)
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Species reactivity (expected):Human.
Species reactivity (tested):Mouse, Rat. -
纯化方法
- Affinity chromatography
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免疫原
- Peptide with sequence KRFQHVIETPEPGK -C, from the N-Terminus of the protein sequence
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应用备注
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Peptide ELISA: 1/8000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0,5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
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别名
- GCKR
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背景
- GCKR is a subfamily member of the SIS (Sugar ISomerase) family of proteins. It is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).Synonyms: GCKR, Glucokinase regulator, Glucokinase regulatory protein
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基因ID
- 2646, 9606
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UniProt
- Q14397
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途径
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
抗原
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