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CPT1C 抗体 (Internal Region)

The 山羊 多克隆 anti-CPT1C antibody (ABIN375150) specifically detects CPT1C in WB. The antibody is reactive with 人, 犬 和 Cow samples.
产品编号 ABIN375150
发货至: 中国
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Quick Overview for CPT1C 抗体 (Internal Region) (ABIN375150)

抗原

See all CPT1C 抗体
CPT1C (Carnitine Palmitoyltransferase 1C (Brain) (CPT1C))

适用

人, 犬, Cow

宿主

  • 52
  • 1
  • 1
山羊

克隆类型

  • 53
  • 1
多克隆

标记

  • 22
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CPT1C antibody is un-conjugated

应用范围

  • 39
  • 27
  • 13
  • 13
  • 10
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 7
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    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
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    Internal Region

    特异性

    This antibody reacts to CPT1C.

    交叉反应 (详细)

    Species reactivity (expected):Canine, Bovine.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    免疫原

    Peptide with sequence C-KSSTKTDSHRLGQH, from the internal region of the protein sequence
  • 应用备注

    Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0,5 mg/mL

    缓冲液

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CPT1C (Carnitine Palmitoyltransferase 1C (Brain) (CPT1C))

    别名

    CPT1C / CPT1-B

    背景

    The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.Synonyms: CPT IC, Carnitine O-palmitoyltransferase 1, Carnitine palmitoyltransferase 1C, brain isoform

    基因ID

    126129, 9606

    UniProt

    Q8TCG5

    途径

    AMPK Signaling, Monocarboxylic Acid Catabolic Process
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