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FAIM 抗体 (Internal Region)

The 山羊 多克隆 anti-FAIM antibody (ABIN375120) specifically detects FAIM in WB 和 IHC (p). The antibody is reactive with 人, 小鼠, 大鼠 和 犬 samples.
产品编号 ABIN375120
发货至: 中国
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Quick Overview for FAIM 抗体 (Internal Region) (ABIN375120)

抗原

See all FAIM 抗体
FAIM (Fas Apoptotic Inhibitory Molecule (FAIM))

适用

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人, 小鼠, 大鼠, 犬

宿主

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山羊

克隆类型

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多克隆

标记

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This FAIM antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    Internal Region

    特异性

    This antibody reacts to all reported isoforms of FAIM1.

    交叉反应 (详细)

    Species reactivity (expected):Mouse, Rat, Canine.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    免疫原

    Peptide with sequence C-KKYMEDRSKTTN, from the internal region of the protein sequence
  • 应用备注

    Peptide ELISA: 1/32000. Western Blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections: 2 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0,5 mg/mL

    缓冲液

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    FAIM (Fas Apoptotic Inhibitory Molecule (FAIM))

    别名

    FAIM

    背景

    FAIM1 (or Fas Apoptotic Inhibitory Molecule 1) is a recently discovered negative regulator of apoptosis. FAIM1 has no significant regions of homology to other gene products that modulate Fas killing. It plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells. Overexpression of FAIM1 diminishes sensitivity to Fas mediated apoptosis of B and non B cell lines. FAIM1 is highly evolutionarily conserved and is widely expressed in murine tissues, suggesting that FAIM1 plays an important role in cellular physiology.Synonyms: FAIM-1, FAIM1, Fas Apoptotic Inhibitory Molecule 1

    基因ID

    55179, 9606

    UniProt

    Q9NVQ4
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