SLC47A1 抗体 (Internal Region)
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北京 101111
Quick Overview for SLC47A1 抗体 (Internal Region) (ABIN375104)
抗原
See all SLC47A1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- C-PEHPQDGAKL SRKQ
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特异性
- This antibody is specific to SLC47A1/MATE-1 (Internal).
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纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography.
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免疫原
- Peptide with sequence from the internal region (near C-Terminus) of the protein sequence according to NP_060712.2.
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anti-Solute Carrier Family 47, Member 1 (SLC47A1) (Internal Region) antibody
Verified SLC47A1 适用: 人 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Solute Carrier Family 47, Member 1 (SLC47A1) (AA 492-519), (C-Term) antibodySLC47A1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB26908 unconjugated
anti-Solute Carrier Family 47, Member 1 (SLC47A1) (AA 492-519) antibodySLC47A1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 47, Member 1 (SLC47A1) (5th Cytoplasmic Loop), (AA 496-509) antibodySLC47A1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 47, Member 1 (SLC47A1) (AA 460-550) antibodySLC47A1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Peptide ELISA: Antibody detection limit dilution 1/64,000. Western Blot: (0.1-0.3 μg/mL)A approx. 60 kDa band is observed in Human Kidney lysates. An additional band of unknownidentity was also consistently observed at 20 kDa. This band was successfully blocked byincubation with the immunizing peptide.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SLC47A1 (Solute Carrier Family 47, Member 1 (SLC47A1))
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别名
- SLC47A1
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背景
- Transporters are expressed in a wide variety of tissues where they perform the critical function of enabling anionic and cationic chemicals of exogenous and endogenous origin to cross otherwise impermeable cell membranes. The multidrug and toxin extrusion (MATE) transporters mediate cellular efflux of a variety of organic cations, including many drugs, and are involved in excretion of toxic electrolytes through urine and bile. Members of the MATE family share homology with the bacterial MATE protein family, which is responsible for drug resistance. MATE1 (multidrug and toxin extrusion protein 1), also known as SLC47A1, is a 570 amino acid multi-pass membrane protein that predominantly localizes to the plasma membrane but is also found in intracellular organelles. Expressed in adrenal gland, and to a lower extent in liver, skeletal muscle and kidney, MATE1 is responsible for the secretion of cationic drugs across the brush border membranes. MATE1 exists as three isoforms, which are produced by alternative splicing events.Synonyms: MATE-1, MATE1, Multidrug and toxin extrusion protein 1, Solute carrier family 47 member 1
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基因ID
- 55244, 9606
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UniProt
- Q96FL8
抗原
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