SULF2 抗体 (Internal Region)
Our Local Distributor
北京 101111
Quick Overview for SULF2 抗体 (Internal Region) (ABIN375090)
抗原
See all SULF2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Internal Region
-
特异性
- This antibody is expected to recognize both reported isoforms (NP_061325.1 and NP_940998.1).
-
纯化方法
- Affinity Chromatography
-
免疫原
- Peptide with sequence C-DGRVYHVGLGDAAQPR, from the internal region of the protein sequence
-
-
anti-Sulfatase 2 (SULF2) (AA 337-654) antibody
SULF2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sulfatase 2 (SULF2) (AA 463-660) antibodySULF2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sulfatase 2 (SULF2) (AA 337-649) antibodySULF2 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sulfatase 2 (SULF2) (C-Term) antibodySULF2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sulfatase 2 (SULF2) (C-Term) antibodySULF2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sulfatase 2 (SULF2) (AA 651-750) antibodySULF2 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sulfatase 2 (SULF2) (AA 801-850) antibodySULF2 适用: 人, Cow, 犬, 马, 兔, Bat, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sulfatase 2 (SULF2) (AA 1-149) antibodySULF2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2H5 unconjugated
anti-Sulfatase 2 (SULF2) (AA 831-860), (C-Term) antibodySULF2 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Peptide ELISA: 1/8000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- Tris saline, pH ~7.3 containing 0.02 % Sodium Azide and 0.5 % BSA
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- SULF2 (Sulfatase 2 (SULF2))
-
别名
- SULF2
-
背景
- Sulf-2 exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin. Mammalian Sulfs are endoproteolytically processed and secreted into the extracellular space of transfected cells, where they exhibit both arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity against intact heparin. Though the molecular weight of full length human Sulf2 is 100455 Da (870 amino acids), the endogenous Sulf2 is found by western blot to be present at molecular weights of 24.4, 33.7 and 51-60 kDa. Higher molecular weight species may be found depending on tissue and/or cell type. Analysis of human tumor tissue and tumor cell lines suggests that HSulf-1 is misregulated in cancers. HSulf-1 is found in a variety of normal tissues but is down-regulated in tumor cell lines originating from ovarian, breast, pancreatic, renal, and hepatocellular carcinoma. Tumors formed by cells expressing Sulf demonstrate enhanced extracellular matrix deposition. The 6-O-sulfation of heparan sulfate of myeloma tumor cells may be a critical factor in determiningand regulating the in vivo growth of this cancer.Synonyms: Extracellular sulfatase Sulf-2, KIAA1247
-
基因ID
- 55959, 9606
-
UniProt
- Q8IWU5
抗原
-
