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MBNL1 抗体 (C-Term)

MBNL1 适用: 人, 大鼠, 小鼠, 犬, Cow WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN375072
发货至: 中国
  • 抗原 See all MBNL1 抗体
    MBNL1 (Muscleblind-like Protein 1 (MBNL1))
    抗原表位
    • 13
    • 10
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 44
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠, 犬, Cow
    宿主
    • 37
    • 6
    • 1
    山羊
    克隆类型
    • 38
    • 6
    多克隆
    标记
    • 22
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MBNL1 antibody is un-conjugated
    应用范围
    • 34
    • 25
    • 7
    • 7
    • 3
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody reacts to MBNL1.
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat, Canine, Bovine.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    免疫原
    Peptide with sequence C-SAEHLTSHKYVTQ, from the C Terminus of the protein sequence
    Top Product
    Discover our top product MBNL1 Primary Antibody
  • 应用备注
    Peptide ELISA: 1/4000. Western Blot: 1 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0,5 mg/mL
    缓冲液
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    MBNL1 (Muscleblind-like Protein 1 (MBNL1))
    别名
    MBNL1 (MBNL1 产品)
    别名
    MBNL1 antibody, zgc:153954 antibody, Mbnl antibody, mKIAA0428 antibody, EXP antibody, EXP35 antibody, EXP40 antibody, EXP42 antibody, MBNL antibody, muscleblind like splicing regulator 1 antibody, muscleblind-like splicing regulator 1 antibody, muscleblind like splicing factor 1 antibody, MBNL1 antibody, mbnl1 antibody, Mbnl1 antibody
    背景
    Muscleblind 1 (MBNL1) binds to the CUG triplet expansion in dsRNA. It appears to play a role in RNA splicing. Several important human diseases are associated with expansion of polynucleotide sequences, in most cases trinucleotide repeats. Myotonic dystrophy (DM1) is one of these diseases, and is associated with increases in the number of CTG repeats in the 3' UTR of the gene encoding myotonin (a.k.a. DM Kinase, DMK or myotonin-Protein Kinase), a ser/thr kinase expressed specifically in muscle. Mammalian genomes contain three muscleblind-like proteins, generally referred to as MBNL1, MBNL2 and MBNL3, and all three were found to associate with long double stranded CUG RNA repeats, thus being triplet repeat expansion dsRNA-binding proteins.Synonyms: EXP, Muscleblind-like protein 1
    基因ID
    4154, 9606
    UniProt
    Q9NR56
    途径
    Ribonucleoprotein Complex Subunit Organization
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