BAG5 抗体 (Internal Region)
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Quick Overview for BAG5 抗体 (Internal Region) (ABIN375061)
抗原
See all BAG5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody reacts to BAG5. This antibody is expected to recognise reported isoform a and isoform b.
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交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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免疫原
- Peptide with sequence DPQGEEKCKAARKQ, from the internal region of the protein sequence
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anti-BCL2-Associated Athanogene 5 (BAG5) (AA 1-447) antibody
BAG5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 5 (BAG5) (AA 198-447) antibodyBAG5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 5 (BAG5) (AA 1-447) antibodyBAG5 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 5 (BAG5) (AA 1-447) antibodyBAG5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E3 unconjugated
anti-BCL2-Associated Athanogene 5 (BAG5) (AA 1-447) antibodyBAG5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 5 (BAG5) antibodyBAG5 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 5 (BAG5) (N-Term) antibodyVerified BAG5 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 5 (BAG5) antibodyKD Validated BAG5 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB3980 unconjugated
anti-BCL2-Associated Athanogene 5 (BAG5) (AA 1-448) antibodyBAG5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E3 unconjugated
anti-BCL2-Associated Athanogene 5 (BAG5) antibodyBAG5 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0,5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- BAG5 (BCL2-Associated Athanogene 5 (BAG5))
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别名
- BAG5
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背景
- BAG5 is a member of the BAG1 related protein family. BAG1 is an anti apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL 2, Raf protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. A BAG domain near the C terminus, may bind and inhibit the chaperone activity of Hsc70/Hsp70. It has been hypothesized that the BAG5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp70's anti apoptotic function. It is believed that BAG5 will play an important role in the mechanisms of neuronal death. BAG5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/modulation of other BAG containing proteins via BAG-BAG heterodimerization.Synonyms: BAG family molecular chaperone regulator 5, BAG-5, Bcl-2-associated athanogene 5, KIAA0873
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基因ID
- 9529, 9606
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UniProt
- Q9UL15
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途径
- SARS-CoV-2 Protein Interactome
抗原
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