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Lactoferrin 抗体 (Internal Region)

There is 1 publication for this product available. The 山羊 多克隆 anti-Lactoferrin antibody is suitable to detect Lactoferrin in samples from 人. It has been validated for WB, IHC (p) 和 EIA.
产品编号 ABIN375038
发货至: 中国
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Quick Overview for Lactoferrin 抗体 (Internal Region) (ABIN375038)

抗原

See all Lactoferrin (LTF) 抗体
Lactoferrin (LTF) (Lactotransferrin (LTF))

适用

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宿主

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山羊

克隆类型

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多克隆

标记

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This Lactoferrin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Internal Region

    序列

    C-ENYKSQQSSD PDP

    特异性

    This antibody detects Lactotransferrin (Internal).

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Immunoaffinity Chromatography

    免疫原

    Peptide with sequence from the internal region of the protein sequence according to NP_002334.2. Genename: LTF
  • 应用备注

    Peptide ELISA: 1/32000. Western Blot: 0.05 - 0.2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • de la Rosa, Yang, Tewary, Varadhachary, Oppenheim: "Lactoferrin acts as an alarmin to promote the recruitment and activation of APCs and antigen-specific immune responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 10, pp. 6868-76, (2008) (PubMed).

  • 抗原

    Lactoferrin (LTF) (Lactotransferrin (LTF))

    别名

    Lactotransferrin

    背景

    Lactoferrin is an 80 kDa non-haem, iron-binding globular glycoprotein and member of the transferrin family present in milk and mucosal secretions, and also released from neutrophil granules during inflammation. LTF acts as a major first line defense against microbial infections, partly due to its ability to efficiently bind to and hence remove Fe3+ from the environment, but studies have also shown that LTF possesses bactericidal properties and proteolytic activity, capable of cleaving arginine-rich sequences within microbial proteins. Three isoforms of LTF have been identified: LTF-alpha, LTF-beta and LTF-gamma and receptors for LTF are expressed in the gastrointestinal tract, by macrophages, lymphocytes, neutrophils and platelets and also by some bacteria.Synonyms: EC=3.4.21, LF, LTF, Lactoferrin, Talalactoferrin

    基因ID

    4057, 9606

    UniProt

    P02788

    途径

    Transition Metal Ion Homeostasis
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