Lactoferrin 抗体 (Internal Region)
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Quick Overview for Lactoferrin 抗体 (Internal Region) (ABIN375038)
抗原
See all Lactoferrin (LTF) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- C-ENYKSQQSSD PDP
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特异性
- This antibody detects Lactotransferrin (Internal).
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- Peptide with sequence from the internal region of the protein sequence according to NP_002334.2. Genename: LTF
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应用备注
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Peptide ELISA: 1/32000. Western Blot: 0.05 - 0.2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "Lactoferrin acts as an alarmin to promote the recruitment and activation of APCs and antigen-specific immune responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 10, pp. 6868-76, (2008) (PubMed).
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- Lactoferrin (LTF) (Lactotransferrin (LTF))
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别名
- Lactotransferrin
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背景
- Lactoferrin is an 80 kDa non-haem, iron-binding globular glycoprotein and member of the transferrin family present in milk and mucosal secretions, and also released from neutrophil granules during inflammation. LTF acts as a major first line defense against microbial infections, partly due to its ability to efficiently bind to and hence remove Fe3+ from the environment, but studies have also shown that LTF possesses bactericidal properties and proteolytic activity, capable of cleaving arginine-rich sequences within microbial proteins. Three isoforms of LTF have been identified: LTF-alpha, LTF-beta and LTF-gamma and receptors for LTF are expressed in the gastrointestinal tract, by macrophages, lymphocytes, neutrophils and platelets and also by some bacteria.Synonyms: EC=3.4.21, LF, LTF, Lactoferrin, Talalactoferrin
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基因ID
- 4057, 9606
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UniProt
- P02788
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途径
- Transition Metal Ion Homeostasis
抗原
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