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ERP29 抗体 (C-Term)

This anti-ERP29 antibody is a 山羊 多克隆 antibody detecting ERP29 in WB. Suitable for 人, 大鼠, 小鼠, 犬, Cow 和 Pig.
产品编号 ABIN375036
发货至: 中国

Quick Overview for ERP29 抗体 (C-Term) (ABIN375036)

抗原

See all ERP29 抗体
ERP29 (Endoplasmic Reticulum Protein 29 (ERP29))

适用

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人, 大鼠, 小鼠, 犬, Cow, Pig

宿主

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山羊

克隆类型

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多克隆

标记

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This ERP29 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    特异性

    This antibody reacts to ERP29.

    交叉反应 (详细)

    Species reactivity (expected):Mouse, Rat, Canine, Bovine, Porcine.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    免疫原

    Peptide with sequence C-EKNKMSDGKKEELQ, from the C-Terminus of the protein sequence
  • 应用备注

    Peptide ELISA: 1/2000. Western Blot: 0.1 - 0.3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0,5 mg/mL

    缓冲液

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    ERP29 (Endoplasmic Reticulum Protein 29 (ERP29))

    别名

    ERP29

    背景

    Proper protein folding and post-translational modifications are essential for secretory protein export out of the endoplasmic reticulum. This task is accomplished by chaperone proteins such as protein disulfide isomerase (PDI), GRP94, and BiP. A recently characterized protein, designated ERp29, is closely related to these chaperone proteins and appears to be upregulated during ER stress conditions. ERp29 is a soluble 259-residue protein that is localized to the lumen of the endoplasmic reticulum in all mammalian cells. Research has shown that there are two primary domains within ERp29. The first is the C-terminal region that is a novel, all helical, fold that is most likely involved with ERp29 retention to the ER. The second is the N-terminal region that resembles that of PDI's thioredoxin module. The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER.Synonyms: C12orf8, ERp28, ERp31, Endoplasmic reticulum protein ERp29

    基因ID

    10961

    NCBI登录号

    NP_006808

    UniProt

    P30040
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