ERN1 抗体 (Internal Region)
(2 references)-
- 抗原 See all ERN1 抗体
- ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠, 犬
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This ERN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody reacts to ERN1 / IRE1a.
- 交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat, Canine, Bovine and Swine.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography
- 免疫原
- Peptide with sequence C-PNAHGKIKAMISD, from the internal region of the protein sequence
- Top Product
- Discover our top product ERN1 Primary Antibody
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anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 401-500) antibody
ERN1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 8D12 unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 401-500) antibodyERN1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D1 unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 282-433) antibodyERN1 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 9F2 unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (pSer726) antibodyERN1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 252-260) antibodyERN1 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (pSer724) antibodyERN1 适用: 人 WB, ELISA, IF 宿主: 兔 Monoclonal 1F12 unconjugated Recombinant Antibody
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (Internal Region) antibodyVerified ERN1 适用: 人 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (C-Term) antibodyERN1 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 493-561) antibodyERN1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Peptide ELISA: 1/8000. Western Blot: 0.03 - 0.1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0,5 mg/mL
- 缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "PKCδ silencing alleviates saturated fatty acid induced ER stress by enhancing SERCA activity." in: Bioscience reports, Vol. 37, Issue 6, (2018) (PubMed).
: "Involvement of selective reactive oxygen species upstream of proapoptotic branches of unfolded protein response." in: The Journal of biological chemistry, Vol. 283, Issue 7, pp. 4252-60, (2008) (PubMed).
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: "PKCδ silencing alleviates saturated fatty acid induced ER stress by enhancing SERCA activity." in: Bioscience reports, Vol. 37, Issue 6, (2018) (PubMed).
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- 抗原
- ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
- 别名
- ERN1 / IRE1 (ERN1 产品)
- 别名
- IRE1 antibody, IRE1P antibody, IRE1a antibody, hIRE1p antibody, 9030414B18Rik antibody, AI225830 antibody, C85377 antibody, Ire1a antibody, Ire1alpha antibody, Ire1p antibody, RGD1559716 antibody, Ern1 antibody, Ire1 antibody, Ire1b antibody, sb:eu1005 antibody, zgc:109932 antibody, endoplasmic reticulum to nucleus signaling 1 antibody, endoplasmic reticulum to nucleus signaling 2 antibody, endoplasmic reticulum (ER) to nucleus signalling 1 antibody, serine/threonine-protein kinase/endoribonuclease IRE1 antibody, endoplasmic reticulum (ER) to nucleus signalling 2 antibody, ERN1 antibody, ERN2 antibody, Ern1 antibody, LOC524719 antibody, Ern2 antibody, ern1 antibody
- 背景
- IRE1 is involved in myo inositol biosynthesis and is implicated as the sensor of unfolded proteins in the ER that initiates transmittance of the unfolded protein signal from the ER to the nucleus. It is a transmembrane protein that has both serine threonine kinase and endoribonuclease activities. Null mutants are viable, but IRE1 is essential for viability under stress conditions that cause unfolded proteins to accumulate in the ER.Synonyms: Endoplasmic reticulum-to-nucleus signaling 1, IRE1a, IRE1p, Inositol-requiring protein 1, Ire1-alpha, Serine/threonine-protein kinase/endoribonuclease IRE1
- 基因ID
- 2081
- NCBI登录号
- NP_001424
- UniProt
- O75460
- 途径
- ER-Nucleus Signaling, Unfolded Protein Response
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