KPNA6 抗体 (Internal Region)
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Quick Overview for KPNA6 抗体 (Internal Region) (ABIN374979)
抗原
See all KPNA6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody detects KPNA6.
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交叉反应 (详细)
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Species reactivity (expected):Mouse, Rat, Dog, Pig, Bovine.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography.
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免疫原
- Peptide with sequence C-STTGESVITREMVE, from the internal of the protein sequence
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应用备注
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Peptide ELISA: 1/128000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))
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别名
- KPNA6 / Importin alpha-7
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背景
- Nucleocytoplasmic transport, a signal and energy dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family.Synonyms: IPOA7, KPNA6, Karyopherin subunit alpha-6
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基因ID
- 23633
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NCBI登录号
- NP_036448
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UniProt
- O60684
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途径
- Protein targeting to Nucleus
抗原
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