PC 抗体 (Internal Region)
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Quick Overview for PC 抗体 (Internal Region) (ABIN374944)
抗原
See all PC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- C-KFKEVKKAYV EANQ
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特异性
- Recognizes Pyruvate Carboxylase (PC).
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交叉反应 （详细）
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Species reactivity (expected):Human, Rat, Canine, Bovine, Porcine.
Species reactivity (tested):Mouse. -
纯化方法
- Affinity Chromatography
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免疫原
- Peptide with sequence from the internal region of the protein sequence according to NP_000911.2, NP_001035806.1 and NP_071504.2.
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anti-Pyruvate Carboxylase (PC) (AA 36-486) antibody
PC 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Carboxylase (PC) (Internal Region) antibodyVerified PC 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Pyruvate Carboxylase (PC) (AA 357-406) antibodyPC 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Carboxylase (PC) (AA 981-1030) antibodyPC 适用: 人, 小鼠, Pig, 犬, 马, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Carboxylase (PC) (AA 52-82), (N-Term) antibodyPC 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Peptide ELISA: 1/16000. Western Blot: 0.03 - 0.1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PC (Pyruvate Carboxylase (PC))
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别名
- Pyruvic Carboxylase (PC)
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背景
- Pyruvate Carboxylase (PC, PCB) requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. PCB is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.Synonyms: PCB, Pyruvate carboxylase mitochondrial
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分子量
- 130kDa (NP_000911.2, NP_001035806.1 and NP_071504.2).
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基因ID
- 5091, 9606
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UniProt
- P11498
抗原
-
