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PC 抗体 (Internal Region)

PC 适用: 人, 小鼠, 大鼠, Pig, Cow, 犬 WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374944
发货至: 中国
  • 抗原 See all PC 抗体
    PC (Pyruvate Carboxylase (PC))
    抗原表位
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 16
    • 15
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Pig, Cow, 犬
    宿主
    • 23
    • 1
    • 1
    山羊
    克隆类型
    • 24
    • 1
    多克隆
    标记
    • 18
    • 2
    • 2
    • 1
    • 1
    • 1
    This PC antibody is un-conjugated
    应用范围
    • 24
    • 17
    • 14
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    C-KFKEVKKAYV EANQ
    特异性
    Recognizes Pyruvate Carboxylase (PC).
    交叉反应 (详细)
    Species reactivity (expected):Human, Rat, Canine, Bovine, Porcine.
    Species reactivity (tested):Mouse.
    纯化方法
    Affinity Chromatography
    免疫原
    Peptide with sequence from the internal region of the protein sequence according to NP_000911.2, NP_001035806.1 and NP_071504.2.
    Top Product
    Discover our top product PC Primary Antibody
  • 应用备注
    Peptide ELISA: 1/16000. Western Blot: 0.03 - 0.1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PC (Pyruvate Carboxylase (PC))
    别名
    Pyruvic Carboxylase (PC) (PC 产品)
    别名
    BcDNA antibody, BcDNA:GH06348 antibody, Dmel\\CG1516 antibody, PC antibody, pyc antibody, wu:fb82g08 antibody, wu:fj85g01 antibody, PCX antibody, BA4157 antibody, Pc antibody, Pcb antibody, PCB antibody, Pcx antibody, Pyruvate carboxylase antibody, pyruvate carboxylase b antibody, PYruvate Carboxylase antibody, pyruvate carboxylase antibody, pyruvate carboxylase Pyr1 antibody, PCB antibody, pcxb antibody, pyc-1 antibody, PC antibody, pyc antibody, pyr1 antibody, CNF00650 antibody, PYC1 antibody, Ndas_1152 antibody, Ilyop_2503 antibody, Calni_0495 antibody, Ftrac_1004 antibody, Plabr_3574 antibody, Sgly_2936 antibody, Celly_0558 antibody, Hipma_0131 antibody, Halhy_1567 antibody, Mesop_1269 antibody, Pcx antibody, Pc antibody
    背景
    Pyruvate Carboxylase (PC, PCB) requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. PCB is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.Synonyms: PCB, Pyruvate carboxylase mitochondrial
    分子量
    130kDa (NP_000911.2, NP_001035806.1 and NP_071504.2).
    基因ID
    5091, 9606
    UniProt
    P11498
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