GALNS 抗体 (Internal Region)
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Quick Overview for GALNS 抗体 (Internal Region) (ABIN374878)
抗原
See all GALNS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- C-TTHNLEDHTK LP
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特异性
- This antibody detects GALNS.
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
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免疫原
- Peptide from the internal region of the protein sequence according to NP_000503.1 Genename: GALNS
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应用备注
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Peptide ELISA: limit dilution 1: 64000. Western blot: 0.01-0.03 μg/mL. Approx 60 kDa band observed in Human Bone Marrow andPlacenta lysates (calculated MW of 58.0 kDa according to NP_000503.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- GALNS (Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS))
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别名
- GALNS
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背景
- GALNS (N-acetylgalactosamine-6-sulfatase) is a lysosomal exohydrolase which catalyzes the hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder.Synonyms: Chondroitinase, Chondroitinsulfatase, EC=3.1.6.4, GalNAc6S sulfatase, Galactose-6-sulfate sulfatase, N-acetylgalactosamine-6-sulfatase, N-acetylgalactosamine-6-sulfate sulfatase
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基因ID
- 2588
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NCBI登录号
- NP_000503
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UniProt
- P34059
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途径
- Glycosaminoglycan Metabolic Process
抗原
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