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ADH5 抗体 (Internal Region)

ADH5 适用: 人, 小鼠, 大鼠, Pig, Cow, 犬 WB, IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374869
发货至: 中国
  • 抗原 See all ADH5 抗体
    ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))
    抗原表位
    • 16
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 43
    • 40
    • 18
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Pig, Cow, 犬
    宿主
    • 60
    • 6
    • 1
    山羊
    克隆类型
    • 64
    • 3
    多克隆
    标记
    • 30
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADH5 antibody is un-conjugated
    应用范围
    • 37
    • 29
    • 16
    • 13
    • 13
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    序列
    C-KKIKVDEFVT HN
    特异性
    This antibody detects Alcohol Dehydrogenase 5 (ADH5).
    交叉反应 (详细)
    Species reactivity (expected):Canine (Dog), Pig, Bovine.
    Species reactivity (tested):Human, Mouse, Rat.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Peptide from the internal region of the protein sequence according to NP_000662.3 Genename: ADH5
    Top Product
    Discover our top product ADH5 Primary Antibody
  • 应用备注
    Peptide ELISA: antibody detection limit dilution 1: 1000. Western blot: 1-3 μg/mL. Customer's experiments gave a band at approx 38 kDa in MouseLymphocyte lysates (calculated MW of 39.8 kDa according to Human NP_000662.3 and39.8 kDa according to Mouse NP_031436.2).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))
    别名
    Alcohol Dehydrogenase 5 (ADH5) (ADH5 产品)
    别名
    ADH2 antibody, ADH-3 antibody, ADHX antibody, FALDH antibody, FDH antibody, GSH-FDH antibody, GSNOR antibody, ADH1C antibody, ADH3 antibody, wu:fb60b11 antibody, Adh-5 antibody, Adh3 antibody, adh-3 antibody, adh3 antibody, adh5 antibody, adhx antibody, fdh antibody, gsnor antibody, ADH4 antibody, ADH5 antibody, alcohol dehydrogenase 1B (class I), beta polypeptide antibody, alcohol dehydrogenase 5 (class III), chi polypeptide antibody, alcohol dehydrogenase 5 antibody, alcohol dehydrogenase 5 (class III), chi polypeptide L homeolog antibody, alcohol dehydrogenase class-3 antibody, ADH1B antibody, ADH5 antibody, adh5 antibody, Adh5 antibody, adh5.L antibody, LOC101112223 antibody
    背景
    The ADH5 gene encodes glutathione dependent formaldehyde dehydrogenase or class III alcohol dehydrogenase chi subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, retinol, ethanol and other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class III alcohol dehydrogenase is a homodimer composed of 2 chi subunits. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long chain primary alcohols and for oxidation of S hydroxymethyl glutathione, a spontaneous adduct between formaldehyde and glutathione. The enzyme is an important component of cellular metabolism for the elimination of formaldehyde, which is a potent irritant and sensitizing agent that causes rhinitis, lacrymation, contact dermatitis and pharyngitis.Synonyms: Alcohol dehydrogenase class 3 chi chain, Glutathione-dependent formaldehyde dehydrogenase, S-(hydroxymethyl)glutathione dehydrogenase
    分子量
    39.7 kDa according to NP_000662.3.
    基因ID
    128, 9606
    UniProt
    P11766
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