DGAT1 抗体 (Internal Region)
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Quick Overview for DGAT1 抗体 (Internal Region) (ABIN374862)
抗原
See all DGAT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- C-QNSMKPFKDM DYS
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特异性
- This antibody recognizes DGAT1.
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交叉反应 (详细)
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Species reactivity (expected):Mouse, Canine (Dog).
Species reactivity (tested):Human, Rat. -
纯化方法
- Immunoaffinity Chromatography
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免疫原
- Peptide with sequence from the internal region of the protein sequence according to NP_036211.1.
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应用备注
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Peptide ELISA: 1/16000. Western Blot: 0.5 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- DGAT1 (Diacylglycerol O-Acyltransferase 1 (DGAT1))
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别名
- DGAT1
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背景
- Glucose and insulin are anabolic signals which upregulate the transcriptions of a series of lipogenic enzymes to convert excess carbohydrate into triglycerides for efficient energy storage. DGAT1 is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. DGAT catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates. DGAT plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism such as intestinal fat absorption, lipoprotein assembly, adipose tissue formation, and lactation. DGAT1 is involved in fat absorption in the intestine and in basal level triglyceride synthesis in adipose tissue, where it is more highly expressed.Synonyms: AGRP1, CAT-related gene product 1, DGAT, DGAT-1, Diacylglycerol O-acyltransferase 1, Diglyceride acyltransferase
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基因ID
- 8694
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NCBI登录号
- NP_036211
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UniProt
- O75907
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途径
- Hormone Transport
抗原
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