DISC1 抗体 (Internal Region)
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Quick Overview for DISC1 抗体 (Internal Region) (ABIN374852)
抗原
See all DISC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody reacts to DISC1. This antibody is expected to recognise isoforms L and Lv only.
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纯化方法
- Affinity chromatography
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免疫原
- Peptide with sequence C-HSEDKRKTPLKVLE, from the internal region of the protein sequence
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应用备注
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Peptide ELISA: 1/128000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0,5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- DISC1 (Disrupted in Schizophrenia 1 (DISC1))
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别名
- DISC1
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背景
- DISC1 (disrupted in schizophrenia 1) is a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. DISC1 is a multifunctional protein that is involved in neurite outgrowth and cortical development, through its interaction with proteins of the centrosome and cytoskeletal system, and is implicated in schizophrenia. Regions of the primate brain which express DISC1, including the hippocampus, lateral septum, amygdala, cerebral cortex, cerebellum and paraventricular hypothalamus, are reported to be involved in schizophrenia in humans.Synonyms: DISC-1, Disrupted in schizophrenia 1 protein, KIAA0457
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基因ID
- 27185
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NCBI登录号
- NP_001012975
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UniProt
- Q9NRI5
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途径
- Regulation of Cell Size
抗原
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