Iba1 抗体 (C-Term, Isoform 1)
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Quick Overview for Iba1 抗体 (C-Term, Isoform 1) (ABIN374779)
抗原
See all Iba1 (IBA1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term, Isoform 1
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序列
- C-YEEKAREKEK P
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特异性
- This antibody is expected to recognise Isoform 1 (NP_116573.1) and Isoform 3 (NP_001614.3) of AIF1.
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交叉反应 (详细)
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Species reactivity (expected):Canine.
Species reactivity (tested):Human. -
纯化方法
- Ammonium Slphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
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免疫原
- Peptide with sequence from the C-Terminus of the protein sequence according to NP_116573.1, NP_001614.3.
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应用备注
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Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL. Immunohistochemistry on paraffin sections: 2 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))
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别名
- AIF1
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背景
- Allograft Inflammatory Factor-1 (AIF1)or ionized calcium-binding adaptor molecule 1 (Iba1) is expressed selectively in microglia/macrophages and is a Ca2+-binding peptide produced by activated monocytes and microglial cells. It has been suggested that AIF1 expression is associated with chronic inflammatory processes. AIF1 is expressed by activated monocytes and might participate in a variety of pathogenic processes in the mammalian brain and in chronic transplant rejection. It has been shown to be expressed early and persistently in chronically rejecting cardiac allografts but not in cardiac syngrafts and host hearts.Synonyms: AIF-1, Allograft inflammatory factor 1, IBA1, Ionized Calcium-Binding Adapter Molecule 1, Protein G1
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基因ID
- 199, 9606
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UniProt
- P55008
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途径
- Smooth Muscle Cell Migration
抗原
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