FH 抗体 (Internal Region)
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北京 101111
Quick Overview for FH 抗体 (Internal Region) (ABIN374767)
抗原
See all FH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- C-HPNDHVNKSQ SSND
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特异性
- This antibody recognizes Fumarase/FH
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交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat and Canine (Dog).
Species reactivity (tested):Human. -
纯化方法
- Immunoaffinity Chromatography
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免疫原
- Peptide with sequence from the internal region of the protein sequence according to NP_000134.2 Genename: FH
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anti-Fumarate Hydratase (FH) (AA 45-188) antibody
FH 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fumarate Hydratase (FH) antibodyFH 适用: 人, 大鼠, 犬 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 1F10 unconjugated
anti-Fumarate Hydratase (FH) antibodyKD Validated FH 适用: 人 WB, FACS, IF (p) 宿主: 小鼠 Monoclonal 24GB13010 unconjugated
anti-Fumarate Hydratase (FH) antibodyKO Validated FH 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Fumarate Hydratase (FH) (Internal Region) antibodyVerified FH 适用: 人 WB, ELISA, IHC, EIA 宿主: 山羊 Polyclonal unconjugated
anti-Fumarate Hydratase (FH) (AA 33-510) antibodyFH 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5C12 unconjugated
anti-Fumarate Hydratase (FH) antibodyFH 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fumarate Hydratase (FH) (AA 33-510) antibodyFH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-Fumarate Hydratase (FH) (AA 33-510) antibodyFH 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3E7 unconjugated
anti-Fumarate Hydratase (FH) (AA 42-185) antibodyFH 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Peptide ELISA: 1/64000. Western Blot: 0.01-0.03 μg/mL. Approx 48 kDa band observed in Human Kidney, Liver andLung lysates. The observed molecular weight corresponds to earlier findings withantibodies from different sources. In transfected HEK293 transiently expressing Fumarasea band of approx.58 kDa is observed. This band is not observed in the non-transfectedHEK293.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3 containing 0.02 % Sodium Azide and 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FH (Fumarate Hydratase (FH))
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别名
- Fumarase
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背景
- FH (Fumarate hydratse) catalyzes the conversion of fumarate to malate. It is a key enzyme in the tricarboxylic acid (TCA) cycle. It exists in a cytosolic form and an N terminal extended form. The N terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. FH also acts as a tumor suppressor.Synonyms: HLRCC, LRCC, MCL, MCUL1, mitochondrial Fumarate hydratase
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分子量
- 54.6 kDa (NP_000134.2).
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基因ID
- 2271, 9606
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UniProt
- P07954
抗原
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