NOD2 抗体 (Internal Region)
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Quick Overview for NOD2 抗体 (Internal Region) (ABIN374736)
抗原
See all NOD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- KFRFTDRERH CSPTD
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特异性
- This antibody recognizes CARD15 / NOD2.
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交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human. -
纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
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免疫原
- Peptide with sequence from the internal region of the protein sequence Genename: CARD15
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anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (N-Term) antibody
NOD2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (AA 251-350) antibodyNOD2 适用: 人 ELISA, WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (AA 460-733) antibodyNOD2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) antibodyNOD2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (AA 1-1040) antibodyNOD2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (C-Term) antibodyNOD2 适用: 人 ELISA, WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (AA 251-350) antibody (AbBy Fluor® 488)NOD2 适用: 人 WB, FACS 宿主: 兔 Polyclonal AbBy Fluor® 488
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (Internal Region) antibodyVerified NOD2 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (AA 1-1040) antibodyNOD2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) antibodyNOD2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Peptide ELISA: 1/64000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % Sodium Azide, pH 7.3 with 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- NOD2 (Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2))
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别名
- CARD15 / NOD2
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背景
- CARD15 (Nod2) is a member of the Nod1/Apaf-1 family of intracellular proteins that contain an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and a C-terminal regulatory domain. CARD15 induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. It also confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Unlike Nod1, this homologue is primary expressed in monocytes. Defects in CARD15 are associated with Blau Syndrome (BS) and Crohn's Disease (CD), and are a cause of susceptibility to ulcerative colitis.Synonyms: Caspase recruitment domain-containing protein 15, IBD1, Inflammatory bowel disease protein 1, Nucleotide-binding oligomerization domain-containing protein 2
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基因ID
- 64127, 9606
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UniProt
- Q9HC29
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途径
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome
抗原
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