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SV2A 抗体 (Internal Region)

This anti-SV2A antibody is a 山羊 多克隆 antibody detecting SV2A in WB. Suitable for 人, 大鼠, 小鼠 和 犬.
产品编号 ABIN374729
发货至: 中国

Quick Overview for SV2A 抗体 (Internal Region) (ABIN374729)

抗原

See all SV2A 抗体
SV2A (Synaptic Vesicle Glycoprotein 2A (SV2A))

适用

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人, 大鼠, 小鼠, 犬

宿主

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山羊

克隆类型

  • 45
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多克隆

标记

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This SV2A antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Internal Region

    特异性

    This antibody recognizes SV2A.

    交叉反应 (详细)

    Species reactivity (expected):Mouse, Human, Canine.
    Species reactivity (tested):Rat.

    纯化方法

    Affinity chromatography

    免疫原

    Peptide with sequence C-TVELYPSDKRTTA, from the internal region of the protein sequence
  • 应用备注

    Peptide ELISA: 1/64000. Western Blot: 0.3-1 μg/mL. Approx 80 kDa band observed in rat brain lysates (calculatedMW of 82.0 kDa according to NP_476558.1 (rat)). An additonal band of unknown identitywas also consistently observed at 20 kDa. This band was successfully blocked byincubation with the immunising peptide.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, 0.02 % Sodium Azide, pH 7.3 with 0.5 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    SV2A (Synaptic Vesicle Glycoprotein 2A (SV2A))

    别名

    SV2A

    背景

    SV2s (Synaptic Vesicle protein 2) are integral membrane glycoproteins present in all synaptic vesicles. They have 12 transmembrane domains predicted by sequence analysis. There are three characterized isoforms, SV2A, SV2B and SV2C. SV2A is expressed ubiquitously throughout the brain. SV2B has a more restricted distribution with varying degrees of coexpression with SV2A. SV2C is more closely related to SV2A but shows a very restricted expression pattern. The highest expression levels were observed in phylogenetically old brain areas like pallidum, the midbrain and the olfactory bulb. SV2A is probably involved in the maintenance of a pool of synaptic vesicles competent for calcium-stimulated exocytosis. SV2A is a highly glycosylated synaptic vesicle protein with homology to transmembrane transporters.Synonyms: KIAA0736, Synaptic vesicle glycoprotein 2A

    基因ID

    9900

    NCBI登录号

    NP_055664

    UniProt

    Q7L0J3
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