CHRM1 抗体 (C-Term)
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Quick Overview for CHRM1 抗体 (C-Term) (ABIN374726)
抗原
See all CHRM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to M1 mAChR / CHRM1.
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交叉反应 (详细)
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Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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免疫原
- Peptide with sequence C-DKRRWRKIPKRPGSVH, from the C Terminus of the protein sequence
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应用备注
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Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))
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别名
- Muscarinic Acetylcholine Receptor M1
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背景
- The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. Muscarinic receptors are so called as they are more sensitive to the effects of the alkaloid muscarine, rather than nicotine.Synonyms: CHRM1, mAChR M1, mAChR-M1
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基因ID
- 1128
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NCBI登录号
- NP_000729
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UniProt
- P11229
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途径
- Synaptic Membrane
抗原
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