COMT 抗体 (Internal Region)
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Quick Overview for COMT 抗体 (Internal Region) (ABIN374718)
抗原
See all COMT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody is expected to recognizes both reported isoforms of COMT (NP_000745.1 and NP_009294.1).
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纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
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免疫原
- Peptide with sequence C-QDIIPQLKKKYDVD, from the internal region of the protein sequence (NP_000745.1 and NP_009294.1). Genename: COMT
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anti-Catechol-O-Methyltransferase (COMT) (Internal Region) antibody
Verified COMT 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Catechol-O-Methyltransferase (COMT) (N-Term) antibodyVerified COMT 适用: 人 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Catechol-O-Methyltransferase (COMT) antibodyKO Validated COMT 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Catechol-O-Methyltransferase (COMT) (AA 52-271) antibodyCOMT 适用: 人, 大鼠, 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Catechol-O-Methyltransferase (COMT) (AA 1-182) antibodyCOMT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G4-1A1 unconjugated
anti-Catechol-O-Methyltransferase (COMT) (AA 52-271) antibodyCOMT 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Catechol-O-Methyltransferase (COMT) (Internal Region) antibodyCOMT 适用: 人, 大鼠, 小鼠, 猴, Cow, Pig, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Catechol-O-Methyltransferase (COMT) (C-Term) antibodyCOMT 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Catechol-O-Methyltransferase (COMT) (AA 1-221) antibodyCOMT 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Catechol-O-Methyltransferase (COMT) (AA 1-221) antibodyCOMT 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Peptide ELISA: Detection Limit Dilution: 1/64000. Western Blot: 0.03-0.1 μg/mL. Approx 28 kDa band and faint 28 kDa band observed inhuman testis lysates (calculated MW of 30.8 kDa according to NP_000745.1 and 24.8 kDaaccording to NP_009294.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- COMT (Catechol-O-Methyltransferase (COMT))
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别名
- COMT
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背景
- Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease.Synonyms: Catechol O-methyltransferase
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基因ID
- 1312, 9606
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UniProt
- P21964
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途径
- Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome
抗原
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