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GPX4 抗体 (C-Term, Isoform A)

GPX4 适用: 人, 小鼠, 大鼠, Cow, Pig WB, IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374711
发货至: 中国
  • 抗原 See all GPX4 抗体
    GPX4 (Glutathione Peroxidase 4 (GPX4))
    抗原表位
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term, Isoform A
    适用
    • 47
    • 36
    • 31
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, Pig
    宿主
    • 47
    • 4
    • 1
    山羊
    克隆类型
    • 38
    • 14
    多克隆
    标记
    • 26
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This GPX4 antibody is un-conjugated
    应用范围
    • 35
    • 18
    • 18
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody is expected to recognize isoform A (NP_002076.2) and isoform C (NP_001034937.1).
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat, Pig, Cow.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatpography
    免疫原
    Peptide with sequence (C-EEPLVIEKDLPHY) from the C-terminus of the protein sequencen (NP_002076.2, NP_001034937.1).
    Top Product
    Discover our top product GPX4 Primary Antibody
  • 应用备注
    ELISA: 1/16000. Western Blot: 0.1 - 0.3 μg/mL. Immunohistochemistry on paraffin sections: 0.3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    GPX4 (Glutathione Peroxidase 4 (GPX4))
    别名
    Glutathione Peroxidase 4 / GPX4 (GPX4 产品)
    别名
    GPx-4 antibody, GSHPx-4 antibody, MCSP antibody, PHGPx antibody, snGPx antibody, snPHGPx antibody, Phgpx antibody, gpx-4 antibody, snGpx antibody, cb563 antibody, cb691 antibody, PHGPxa antibody, sb:cb563 antibody, zgc:92253 antibody, wu:fb82e03 antibody, 1700027O09Rik antibody, mtPHGPx antibody, ATGPX4 antibody, F11L15.5 antibody, glutathione peroxidase 4 antibody, GP-GPx4 antibody, glutathione peroxidase 4 antibody, glutathione peroxidase 4a antibody, GPX4 antibody, Gpx4 antibody, gpx4a antibody
    背景
    Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPx family to be discovered. GPx2, also known as gastrointestinal GPx (GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract. Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxy lipids in low density lipoprotein or thymine. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, possess selenocysteine at the active site.Synonyms: GPx-4, Phospholipid hydroperoxide glutathione peroxidase mitochondrial
    基因ID
    2879
    NCBI登录号
    NP_001034936
    UniProt
    P36969
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