HSD11B1 抗体 (C-Term)
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Quick Overview for HSD11B1 抗体 (C-Term) (ABIN374673)
抗原
See all HSD11B1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to HSD3B1.
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纯化方法
- Affinity chromatography
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免疫原
- Peptide with sequence C-DRHKETLKSKTQ, from the C Terminus of the protein sequence
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应用备注
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Peptide ELISA: 1/128000. Western Blot: 0.01 - 0.1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
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别名
- 3-beta-HSD1 / HSD3B1
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背景
- HSD3B1 (3-beta hydroxysteroid dehydrogenase) is a bifunctional enzyme that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. There are two HSD3B1 proteins, type I and type II. Expressed by different genes, they function in different areas of the body. HSD3B1 has been shown to be a highly specific and sensitive trophoblast-associated marker (Mao et. al).Synonyms: 3-beta-hydroxysteroid dehydrogenase, Delta 5-->4-isomerase type 1, Trophoblast Marker
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基因ID
- 3283
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NCBI登录号
- NP_000853
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UniProt
- P14060
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途径
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Carbohydrate Metabolic Process
抗原
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